Hardness Test

Hardness is also so called crushing strength. It is the load required to crush the tablet when placed on its edge. There are a variety of presentations for tablets as delivery systems for pharmaceutical agents, such as rapidly disintegrating, slowly disintegrating, eroding, chewable, and lozenge. Each of these presentations places a certain demand on the bonding, structure, and integrity of the compressed matrix. Tablets must be able to...

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Content Uniformity

Content Uniformity Testing is useful for assessing the consistency of:Powder blends before filling or compressingSemi-solid and liquid bulk batches before fillingFilling during manufacturing (such as powders into capsules or liquids into vials or bottles)Active content within individual units post-manufacturing (such as individual tablets after compression)Content uniformity testing involves using a content/potency assay to determine the content...

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Assay

An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology, and molecular biology for qualitatively assessing or quantitatively measuring the presence or amount or the functional activity of a target entity (the analyte) which can be a drug or biochemical substance or a cell in an organism or organic sample.Generally in an assay the quantity of the exogenous materials (the reagents) are kept fixed...

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Disintegration

Disintegration is a state in which no residues except fragments of un-dissolved coating remain on the screen of test apparatus. If any residue left, it must consists of soft mass having no palpably firm un-moistened core. Purpose:This is the test that is used to check whether your dosage form will disintegrate within the prescribed time when placed in liquid under prescribed experimental conditions. Components:1.      Beaker2.      Thermostat3.      Lever4.      Basket/...

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