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Sunday, April 29, 2012
Gastro Resistant Tablets
This type of dosage form is to be opted when API release is desired in stomach (Antacids, APIs used against H.pylori infection) or site of absorption is either stomach or upper part of small intestine...
Effervescent Tablets
The oral dosage forms are the most popular way of taking medication despite having some disadvantages like slow absorption and thus onset of action is prolong. This can be overcome by administrating the drug in liquid from but, many APIs have limited level of stability in liquid form. So, effervescent tablets acts as an alternative dosage form. The tablet is added into a glass of water just before administration and the drug...
Hypodermic Tablets
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These tablets contain one or more readily water soluble ingredients and are intended to be added in water for injection of sterile water to form a clear solution which is to be injected parenterally. They were widely used by rural physician due to its portability. One bottle of sterile water was carried by the doctor to prepare many types of injectables. It can be used for medicaments whose stability in water is very...
Sub-Lingual Tablets
Completeness of drug absorption is desired but fast drug absorption is not intended. The tablets are designed not to disintegrate. They are flat elliptical or capsule shaped tablets as it can be easily held between gum and cheek. It’s placed near the opening of parotid duct to provide the medium to dissolve the tablet...
Dispersable Tablets
These tablets disintegrate either rapidly in water, to form a stabilized suspension, or disperse instantaneously in the mouth to be swallowed without the aid of water. So, it’s preferred for pediatric patients who cannot swallow a solid dosage form and the API is unstable if formulated in liquid formulation. Also helpful for patients having prolonged illness who are prone to nauseatic sensations if they have to swallow a...
Film Coated Tablets
These are compressed tablets that are covered with a thin layer or film of a water soluble material. a number of polymeric substances with film-forming properties may be used. Film coating imparts the same general characteristics as sugar coating with the added advantage of a greatly reduced time period required for the coating operation. Advantages in material scince and polymer chemistry has made these coatings the first choice of formulatto...
Sugar Coated Tablets
Sugar Coated Tablets are compressed tablets surrounded by a sugar coating. Such coatings may be colored and are beneficial in covering up durgs substances processing objectionable tastes or odours and in protecting materials sensitive to oxidation. these coatings were once quite common and genrally lost commercial appeal due to the high cost of process validation. Recently, they have made a comeback due to patient popularity and technical advanc...
Chewable Tablets
The patients who have difficulty in swallowing tablets whole or for children who have not yet learnt to swallow a tablet, chewable tablet serves as an attractive alternative. The added advantage of this medication is that it can be taken at any time or when water is not available. Mannitol is normally used as a base due to low hygroscopy and more importantly, it gives pleasant, cooling sensation. Antacid tablets are invariably...
Saturday, April 21, 2012
Compressed Tablets
According to Remington these tablets are formed by compression and in their siplest form, contain no special coating. they are maded from powdered, crystalline or granular materials, alone or in combination with binders, disintegrants, controlled-release polymers, lubricants, diluents and in many cases colorants. the vasr majority of tablets commercialized today are compressed tablets, either in an uncoated or coated sta...
